Targeting an RNA-binding Protein Network in Acute Myeloid Leukemia

RNA-binding proteins (RBPs) are essential modulators of transcription and translation frequently dysregulated in cancer. We systematically interrogated RBP dependencies in human cancers using a comprehensive CRISPR/Cas9 domain-focused screen targeting RNA-binding domains of 490 classical RBPs. This...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cancer Cell
Hoofdauteurs: Wang, Eric, Lu, Sydney X., Pastore, Alessandro, Chen, Xufeng, Imig, Jochen, Lee, Stanley Chun-Wei, Hockemeyer, Kathryn, Ghebrechristos, Yohana E., Yoshimi, Akihide, Inoue, Daichi, Ki, Michelle, Cho, Hana, Bitner, Lillian, Kloetgen, Andreas, Lin, Kuan-Ting, Uehara, Taisuke, Owa, Takashi, Tibes, Raoul, Krainer, Adrian R., Abdel-Wahab, Omar, Aifantis, Iannis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424627/
https://ncbi.nlm.nih.gov/pubmed/30799057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.01.010
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items