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Molecular Pathways: Understanding and Targeting Mutant Spliceosomal Proteins

Splicing of precursor messenger RNA is a critical step in regulating gene expression and major advances are being made in understanding the composition and structure of the enzymatic complex which performs splicing, termed the spliceosome. In parallel, there has been increased appreciation for diver...

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Detalles Bibliográficos
Publicado en:Clin Cancer Res
Main Authors: Yoshimi, Akihide, Abdel-Wahab, Omar
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241248/
https://ncbi.nlm.nih.gov/pubmed/27836865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0131
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