Rapidly proliferating CD44(hi) peripheral T cells undergo apoptosis and delay posttransplantation T-cell reconstitution after allogeneic bone marrow transplantation

Delayed T-cell recovery is an important complication of allogeneic bone marrow transplantation (BMT). We demonstrate in murine models that donor BM-derived T cells display increased apoptosis in recipients of allogeneic BMT with or without GVHD. Although this apoptosis was associated with a loss of...

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Detalhes bibliográficos
Main Authors: Alpdogan, S. Önder, Lu, Sydney X., Patel, Neel, McGoldrick, Suzanne, Suh, David, Budak-Alpdogan, Tulin, Smith, Odette M., Grubin, Jeremy, King, Christopher, Goldberg, Gabrielle L., Hubbard, Vanessa M., Kochman, Adam A., van den Brink, Marcel R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597141/
https://ncbi.nlm.nih.gov/pubmed/18815289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-142737
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