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Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors
We present a strategy for adoptive immunotherapy using T-lineage committed lymphoid precursor cells generated by Notch1-based culture. We found that allogeneic T-cell precursors can be transferred to irradiated individuals irrespective of major histocompatibility complex (MHC) disparities and give r...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731996/ https://ncbi.nlm.nih.gov/pubmed/18376399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1395 |
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