Cytolytic T cells induce ceramide-rich platforms in target cell membranes to initiate graft-versus-host disease

Alloreactive donor cytolytic T lymphocytes play a critical role in pathophysiology of acute graft-versus-host disease (GVHD). As GVHD progression involves tumor necrosis factor superfamily receptor activation, and as apoptotic signaling for some tumor necrosis factor superfamily receptors might invo...

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Bibliografski detalji
Glavni autori: Rotolo, Jimmy A., Stancevic, Branka, Lu, Sydney X., Zhang, Jianjun, Suh, David, King, Christopher G., Kappel, Lucy W., Murphy, George F., Liu, Chen, Fuks, Zvi, van den Brink, Marcel R., Kolesnick, Richard
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Transplantation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766684/
https://ncbi.nlm.nih.gov/pubmed/19666872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-191148
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