Cytolytic T cells induce ceramide-rich platforms in target cell membranes to initiate graft-versus-host disease

Alloreactive donor cytolytic T lymphocytes play a critical role in pathophysiology of acute graft-versus-host disease (GVHD). As GVHD progression involves tumor necrosis factor superfamily receptor activation, and as apoptotic signaling for some tumor necrosis factor superfamily receptors might invo...

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Bibliografische gegevens
Hoofdauteurs: Rotolo, Jimmy A., Stancevic, Branka, Lu, Sydney X., Zhang, Jianjun, Suh, David, King, Christopher G., Kappel, Lucy W., Murphy, George F., Liu, Chen, Fuks, Zvi, van den Brink, Marcel R., Kolesnick, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2009
Onderwerpen:
Transplantation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766684/
https://ncbi.nlm.nih.gov/pubmed/19666872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-191148
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