Adoptively transferred TRAIL(+) T cells suppress GVHD and augment antitumor activity

Current strategies to suppress graft-versus-host disease (GVHD) also compromise graft-versus-tumor (GVT) responses. Furthermore, most experimental strategies to separate GVHD and GVT responses merely spare GVT function without actually enhancing it. We have previously shown that endogenously express...

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Главные авторы: Ghosh, Arnab, Dogan, Yildirim, Moroz, Maxim, Holland, Amanda M., Yim, Nury L., Rao, Uttam K., Young, Lauren F., Tannenbaum, Daniel, Masih, Durva, Velardi, Enrico, Tsai, Jennifer J., Jenq, Robert R., Penack, Olaf, Hanash, Alan M., Smith, Odette M., Piersanti, Kelly, Lezcano, Cecilia, Murphy, George F., Liu, Chen, Palomba, M. Lia, Sauer, Martin G., Sadelain, Michel, Ponomarev, Vladimir, van den Brink, Marcel R.M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668849/
https://ncbi.nlm.nih.gov/pubmed/23676461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66301
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