Adoptively transferred TRAIL(+) T cells suppress GVHD and augment antitumor activity

Current strategies to suppress graft-versus-host disease (GVHD) also compromise graft-versus-tumor (GVT) responses. Furthermore, most experimental strategies to separate GVHD and GVT responses merely spare GVT function without actually enhancing it. We have previously shown that endogenously express...

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Autors principals: Ghosh, Arnab, Dogan, Yildirim, Moroz, Maxim, Holland, Amanda M., Yim, Nury L., Rao, Uttam K., Young, Lauren F., Tannenbaum, Daniel, Masih, Durva, Velardi, Enrico, Tsai, Jennifer J., Jenq, Robert R., Penack, Olaf, Hanash, Alan M., Smith, Odette M., Piersanti, Kelly, Lezcano, Cecilia, Murphy, George F., Liu, Chen, Palomba, M. Lia, Sauer, Martin G., Sadelain, Michel, Ponomarev, Vladimir, van den Brink, Marcel R.M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668849/
https://ncbi.nlm.nih.gov/pubmed/23676461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66301
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