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Adoptively transferred TRAIL(+) T cells suppress GVHD and augment antitumor activity

Current strategies to suppress graft-versus-host disease (GVHD) also compromise graft-versus-tumor (GVT) responses. Furthermore, most experimental strategies to separate GVHD and GVT responses merely spare GVT function without actually enhancing it. We have previously shown that endogenously express...

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Bibliografische gegevens
Hoofdauteurs: Ghosh, Arnab, Dogan, Yildirim, Moroz, Maxim, Holland, Amanda M., Yim, Nury L., Rao, Uttam K., Young, Lauren F., Tannenbaum, Daniel, Masih, Durva, Velardi, Enrico, Tsai, Jennifer J., Jenq, Robert R., Penack, Olaf, Hanash, Alan M., Smith, Odette M., Piersanti, Kelly, Lezcano, Cecilia, Murphy, George F., Liu, Chen, Palomba, M. Lia, Sauer, Martin G., Sadelain, Michel, Ponomarev, Vladimir, van den Brink, Marcel R.M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668849/
https://ncbi.nlm.nih.gov/pubmed/23676461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66301
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