Overcoming immunological barriers in regenerative medicine

af Zakrzewski, Johannes L, van den Brink, Marcel R M, Hubbell, Jeffrey A
Udgivet i Nat Biotechnol (2014)

Enhancing T cell reconstitution after hematopoietic stem cell transplantation: a brief update of the latest trends

af Zakrzewski, Johannes L., Goldberg, Gabrielle L., Smith, Odette M., van den Brink, Marcel R.M.
Udgivet 2007

Clinical Strategies to Enhance T cell Reconstitution

af Goldberg, Gabrielle L, Zakrzewski, Johannes L, Perales, Miguel A, van den Brink, Marcel R.M.
Udgivet 2007

Free-hand ultrasound guidance permits safe and efficient minimally invasive intrathymic injections in both young and aged mice

af Tuckett, Andrea Z., Zakrzewski, Johannes L., Li, Duan, van den Brink, Marcel R.M., Thornton, Raymond H.
Udgivet i Ultrasound Med Biol (2015)

Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man

af Holland, Amanda M., Zakrzewski, Johannes L., Goldberg, Gabrielle L., Ghosh, Arnab, van den Brink, Marcel R. M.
Udgivet i Semin Immunopathol (2008)

Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency

af Tuckett, Andrea Z., Thornton, Raymond H., O’Reilly, Richard J., van den Brink, Marcel R. M., Zakrzewski, Johannes L.
Udgivet i J Hematol Oncol (2017)

Image-guided intrathymic injection of multipotent stem cells supports lifelong T-cell immunity and facilitates targeted immunotherapy

af Tuckett, Andrea Z., Thornton, Raymond H., Shono, Yusuke, Smith, Odette M., Levy, Emily R., Kreines, Fabiana M., van den Brink, Marcel R. M., Zakrzewski, Johannes L.
Udgivet 2014

Targeting metabolism and survival in chronic lymphocytic leukemia and Richter syndrome cells by a novel NF-κB inhibitor

af Vaisitti, Tiziana, Gaudino, Federica, Ouk, Samedy, Moscvin, Maria, Vitale, Nicoletta, Serra, Sara, Arruga, Francesca, Zakrzewski, Johannes L., Liou, Hsiou-Chi, Allan, John N., Furman, Richard R., Deaglio, Silvia
Udgivet i Haematologica (2017)

Extrathymic development of murine T cells after bone marrow transplantation

af Holland, Amanda M., Zakrzewski, Johannes L., Tsai, Jennifer J., Hanash, Alan M., Dudakov, Jarrod A., Smith, Odette M., West, Mallory L., Singer, Natalie V., Brill, Jessie, Sun, Joseph C., van den Brink, Marcel R.M.
Udgivet 2012

Organ-derived dendritic cells have differential effects on alloreactive T cells

af Kim, Theo D., Terwey, Theis H., Zakrzewski, Johannes L., Suh, David, Kochman, Adam A., Chen, Megan E., King, Chris G., Borsotti, Chiara, Grubin, Jeremy, Smith, Odette M., Heller, Glenn, Liu, Chen, Murphy, George F., Alpdogan, Onder, van den Brink, Marcel R. M.
Udgivet 2008

CCR2 is required for CD8-induced graft-versus-host disease

af Terwey, Theis H., Kim, Theo D., Kochman, Adam A., Hubbard, Vanessa M., Lu, Sydney, Zakrzewski, Johannes L., Ramirez-Montagut, Teresa, Eng, Jeffrey M., Muriglan, Stephanie J., Heller, Glenn, Murphy, George F., Liu, Chen, Budak-Alpdogan, Tulin, Alpdogan, Onder, van den Brink, Marcel R. M.
Udgivet 2005

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease

af Lu, Sydney X., Alpdogan, Onder, Lin, Janine, Balderas, Robert, Campos-Gonzalez, Roberto, Wang, Xiao, Gao, Guo-Jian, Suh, David, King, Christopher, Chow, Melanie, Smith, Odette M., Hubbard, Vanessa M., Bautista, Johanne L., Cabrera-Perez, Javier, Zakrzewski, Johannes L., Kochman, Adam A., Chow, Andrew, Altan-Bonnet, Gregoire, van den Brink, Marcel R. M.
Udgivet 2008

Sex steroid blockade enhances thymopoiesis by modulating Notch signaling

af Velardi, Enrico, Tsai, Jennifer J., Holland, Amanda M., Wertheimer, Tobias, Yu, Vionnie W.C., Zakrzewski, Johannes L., Tuckett, Andrea Z., Singer, Natalie V., West, Mallory L., Smith, Odette M., Young, Lauren F., Kreines, Fabiana M., Levy, Emily R., Boyd, Richard L., Scadden, David T., Dudakov, Jarrod A., van den Brink, Marcel R.M.
Udgivet i J Exp Med (2014)

Characterization of a c-Rel inhibitor that mediates anticancer properties in hematologic malignancies by blocking NF-κB-controlled oxidative stress responses

af Shono, Yusuke, Tuckett, Andrea Z., Liou, Hsiou-Chi, Doubrovina, Ekaterina, Derenzini, Enrico, Ouk, Samedy, Tsai, Jennifer J., Smith, Odette M., Levy, Emily R., Kreines, Fabiana M., Ziegler, Carly G.K., Scallion, Mary I., Doubrovin, Mikhail, Heller, Glenn, Younes, Anas, O’Reilly, Richard J., van den Brink, Marcel R.M., Zakrzewski, Johannes L.
Udgivet i Cancer Res (2016)

A small molecule c-Rel inhibitor reduces alloactivation of T-cells without compromising anti-tumor activity

af Shono, Yusuke, Tuckett, Andrea Z, Ouk, Samedy, Liou, Hsiou-Chi, Altan-Bonnet, Grégoire, Tsai, Jennifer J, Oyler, Jennifer E, Smith, Odette M, West, Mallory L, Singer, Natalie V, Doubrovina, Ekaterina, Pankov, Dmitry, Undhad, Chandresh V, Murphy, George F, Lezcano, Cecilia, Liu, Chen, O’Reilly, Richard J, van den Brink, Marcel RM, Zakrzewski, Johannes L
Udgivet 2014

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation

af Jenq, Robert R., King, Christopher G., Volk, Christine, Suh, David, Smith, Odette M., Rao, Uttam K., Yim, Nury L., Holland, Amanda M., Lu, Sydney X., Zakrzewski, Johannes L., Goldberg, Gabrielle L., Diab, Adi, Alpdogan, Onder, Penack, Olaf, Na, Il-Kang, Kappel, Lucy W., Wolchok, Jedd D., Houghton, Alan N., Perales, Miguel-Angel, van den Brink, Marcel R. M.
Udgivet 2009

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

af Zakrzewski, Johannes L, Suh, David, Markley, John C, Smith, Odette M, King, Christopher, Goldberg, Gabrielle L, Jenq, Robert, Holland, Amanda M, Grubin, Jeremy, Cabrera-Perez, Javier, Brentjens, Renier J, Lu, Sydney X, Rizzuto, Gabrielle, Sant’Angelo, Derek B, Riviere, Isabelle, Sadelain, Michel, Heller, Glenn, Zúñiga-Pflücker, Juan Carlos, Lu, Chen, van den Brink, Marcel R M
Udgivet 2008

Absence of P-selectin in Recipients of Allogeneic Bone Marrow Transplantation Ameliorates Experimental Graft-versus-Host-Disease

af Lu, Sydney X., Holland, Amanda M., Na, Il-Kang, Terwey, Theis H., Alpdogan, Onder, Bautista, Jhoanne L., Smith, Odette M., Suh, David, King, Christopher, Kochman, Adam, Hubbard, Vanessa M., Rao, Uttam K., Yim, Nury, Liu, Chen, Laga, Alvaro C., Murphy, George, Jenq, Robert, Zakrzewski, Johannes L., Penack, Olaf, Dykstra, Lindsay, Bampoe, Kevin, Perez, Lia, Furie, Bruce, Furie, Barbara, van den Brink, Marcel R.M.
Udgivet 2010

Donor CD19-CAR T Cells Exert Potent Graft-versus-Lymphoma Activity With Diminished Graft-versus-Host Activity

af Ghosh, Arnab, Smith, Melody, James, Scott E., Davila, Marco L., Velardi, Enrico, Argyropoulos, Kimon V., Gunset, Gertrude, Perna, Fabiana, Kreines, Fabiana M., Levy, Emily R., Lieberman, Sophie, Jay, Hilary, Tuckett, Andrea Z., Zakrzewski, Johannes L., Tan, Lisa, Young, Lauren F., Takvorian, Kate, Dudakov, Jarrod A., Jenq, Robert R., Hanash, Alan M., Motta, Ana Carolina F., Murphy, George F., Liu, Chen, Schietinger, Andrea, Sadelain, Michel, van den Brink, Marcel R.M.
Udgivet i Nat Med (2017)

c-Rel orchestrates energy-dependant epithelial and macrophage reprogramming in fibrosis

af Leslie, Jack, Macia, Marina García, Luli, Saimir, Worrell, Julie C., Reilly, William J, Paish, Hannah L, Knox, Amber, Barksby, Ben S, Gee, Lucy M, Zaki, Marco Y.W., Collins, Amy, Burgoyne, Rachel A, Cameron, Rainie, Bragg, Charlotte, Xu, Xin, Chung, Git W, Brown, Colin DA, Blanchard, Andrew D, Nanthakumar, Carmel B, Karsdal, Morten, Robinson, Stuart M, Manas, Derek M, Sen, Gourab, French, Jeremy, White, Steven A, Murphy, Sandra, Trost, Matthias, Zakrzewski, Johannes L, Klein, Ulf, Schwabe, Robert F, Mederacke, Ingmar, Nixon, Colin, Bird, Tom, Teuwen, Laure-Anne, Schoonjans, Luc, Carmeliet, Peter, Mann, Jelena, Fisher, Andrew J, Sheerin, Neil S, Borthwick, Lee A, Mann, Derek A, Oakley, Fiona
Udgivet i Nat Metab (2020)