The Puzzle of RNAs that Target Gene Promoters

di Younger, Scott T., Corey, David R.
Pubblicazione 2009

Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

di Younger, Scott T., Corey, David R.
Pubblicazione 2011

'Lnc'-ing enhancers to MYC regulation

di Younger, Scott T, Rinn, John L
Pubblicazione 2014

Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini()

di Younger, Scott T., Corey, David R.
Pubblicato in Mol Biosyst (2011)

Silent pericentromeric repeats speak out

di Younger, Scott T., Rinn, John L.
Pubblicato in Proc Natl Acad Sci U S A (2015)

p53 regulates enhancer accessibility and activity in response to DNA damage

di Younger, Scott T., Rinn, John L.
Pubblicato in Nucleic Acids Res (2017)

Identification of functional regulatory elements in the human genome using pooled CRISPR screens

di Borys, Samantha M., Younger, Scott T.
Pubblicato in BMC Genomics (2020)

Predicting potential miRNA target sites within gene promoters

di Younger, Scott T., Pertsemlidis, Alexander, Corey, David R.
Pubblicazione 2009

CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo

di Shechner, David M., Hacisüleyman, Ezgi, Younger, Scott T., Rinn, John L.
Pubblicato in Nat Methods (2015)

Expediting rare disease diagnosis: a call to bridge the gap between clinical and functional genomics

di Hartin, Samantha N., Means, John C., Alaimo, Joseph T., Younger, Scott T.
Pubblicato in Mol Med (2020)

FOXC2 Autoregulates Its Expression in the Pulmonary Endothelium After Endotoxin Stimulation in a Histone Acetylation-Dependent Manner

di Xia, Sheng, Yu, Wei, Menden, Heather, Younger, Scott T., Sampath, Venkatesh
Pubblicato in Front Cell Dev Biol (2021)

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

di Chu, Yongjun, Yue, Xuan, Younger, Scott T., Janowski, Bethany A., Corey, David R.
Pubblicazione 2010

Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage

di Younger, Scott T., Kenzelmann-Broz, Daniela, Jung, Heiyoun, Attardi, Laura D., Rinn, John L.
Pubblicato in Nucleic Acids Res (2015)

Regulation of Transcription by Small RNAs Complementary to Sequences Downstream from the 3’ Termini of Genes

di Yue, Xuan, Schwartz, Jacob C., Younger, Scott T., Chu, Yongjun, Gagnon, Keith T., Elbashir, Sayda, Janowski, Bethany A., Corey, David R.
Pubblicazione 2010

Antisense transcripts are targets for activating small RNAs

di Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Pubblicazione 2008

Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction

di Younger, Scott, Jang, Hyunbum, Davies, Hannah A., Niemiec, Martin J., Garcia, Joe G.N., Nussinov, Ruth, Migrino, Raymond Q., Madine, Jillian, Arce, Fernando T.
Pubblicato in Biophys J (2020)

Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens

di Najm, Fadi J, Strand, Christine, Donovan, Katherine F, Hegde, Mudra, Sanson, Kendall R, Vaimberg, Emma W, Sullender, Meagan E, Hartenian, Ella, Kalani, Zohra, Fusi, Nicolo, Listgarten, Jennifer, Younger, Scott T, Bernstein, Bradley E, Root, David E, Doench, John G
Pubblicato in Nat Biotechnol (2017)

Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion

di Harris, Isaac S., Endress, Jennifer E., Coloff, Jonathan L., Selfors, Laura M., McBrayer, Samuel K., Rosenbluth, Jennifer M., Takahashi, Nobuaki, Dhakal, Sabin, Koduri, Vidyasagar, Oser, Matthew G., Schauer, Nathan J., Doherty, Laura M., Hong, Andrew L., Kang, Yun Pyo, Younger, Scott T., Doench, John G., Hahn, William C., Buhrlage, Sara J., DeNicola, Gina M., Kaelin, William G., Brugge, Joan S.
Pubblicato in Cell Metab (2019)

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

di Dempster, Joshua M., Pacini, Clare, Pantel, Sasha, Behan, Fiona M., Green, Thomas, Krill-Burger, John, Beaver, Charlotte M., Younger, Scott T., Zhivich, Victor, Najgebauer, Hanna, Allen, Felicity, Gonçalves, Emanuel, Shepherd, Rebecca, Doench, John G., Yusa, Kosuke, Vazquez, Francisca, Parts, Leopold, Boehm, Jesse S., Golub, Todd R., Hahn, William C., Root, David E., Garnett, Mathew J., Tsherniak, Aviad, Iorio, Francesco
Pubblicato in Nat Commun (2019)

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

di Marinaccio, Christian, Suraneni, Praveen, Celik, Hamza, Volk, Andrew, Wen, Qiang Jeremy, Ling, Te, Bulic, Marinka, Lasho, Terra, Koche, Richard P., Famulare, Christopher A., Farnoud, Noushin, Stein, Brady, Schieber, Michael, Gurbuxani, Sandeep, Root, David E., Younger, Scott T., Hoffman, Ronald, Gangat, Naseema, Ntziachristos, Panagiotis, Chandel, Navdeep S., Levine, Ross L, Rampal, Raajit K., Challen, Grant A., Tefferi, Ayalew, Crispino, John D.
Pubblicato in Cancer Discov (2021)