The Puzzle of RNAs that Target Gene Promoters

by Younger, Scott T., Corey, David R.
Published 2009

Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

by Younger, Scott T., Corey, David R.
Published 2011

'Lnc'-ing enhancers to MYC regulation

by Younger, Scott T, Rinn, John L
Published 2014

Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini()

by Younger, Scott T., Corey, David R.
Published in Mol Biosyst (2011)

Silent pericentromeric repeats speak out

by Younger, Scott T., Rinn, John L.
Published in Proc Natl Acad Sci U S A (2015)

p53 regulates enhancer accessibility and activity in response to DNA damage

by Younger, Scott T., Rinn, John L.
Published in Nucleic Acids Res (2017)

Identification of functional regulatory elements in the human genome using pooled CRISPR screens

by Borys, Samantha M., Younger, Scott T.
Published in BMC Genomics (2020)

Predicting potential miRNA target sites within gene promoters

by Younger, Scott T., Pertsemlidis, Alexander, Corey, David R.
Published 2009

CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo

by Shechner, David M., Hacisüleyman, Ezgi, Younger, Scott T., Rinn, John L.
Published in Nat Methods (2015)

Expediting rare disease diagnosis: a call to bridge the gap between clinical and functional genomics

by Hartin, Samantha N., Means, John C., Alaimo, Joseph T., Younger, Scott T.
Published in Mol Med (2020)

FOXC2 Autoregulates Its Expression in the Pulmonary Endothelium After Endotoxin Stimulation in a Histone Acetylation-Dependent Manner

by Xia, Sheng, Yu, Wei, Menden, Heather, Younger, Scott T., Sampath, Venkatesh
Published in Front Cell Dev Biol (2021)

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

by Chu, Yongjun, Yue, Xuan, Younger, Scott T., Janowski, Bethany A., Corey, David R.
Published 2010

Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage

by Younger, Scott T., Kenzelmann-Broz, Daniela, Jung, Heiyoun, Attardi, Laura D., Rinn, John L.
Published in Nucleic Acids Res (2015)

Regulation of Transcription by Small RNAs Complementary to Sequences Downstream from the 3’ Termini of Genes

by Yue, Xuan, Schwartz, Jacob C., Younger, Scott T., Chu, Yongjun, Gagnon, Keith T., Elbashir, Sayda, Janowski, Bethany A., Corey, David R.
Published 2010

Antisense transcripts are targets for activating small RNAs

by Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Published 2008

Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction

by Younger, Scott, Jang, Hyunbum, Davies, Hannah A., Niemiec, Martin J., Garcia, Joe G.N., Nussinov, Ruth, Migrino, Raymond Q., Madine, Jillian, Arce, Fernando T.
Published in Biophys J (2020)

Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens

by Najm, Fadi J, Strand, Christine, Donovan, Katherine F, Hegde, Mudra, Sanson, Kendall R, Vaimberg, Emma W, Sullender, Meagan E, Hartenian, Ella, Kalani, Zohra, Fusi, Nicolo, Listgarten, Jennifer, Younger, Scott T, Bernstein, Bradley E, Root, David E, Doench, John G
Published in Nat Biotechnol (2017)

Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion

by Harris, Isaac S., Endress, Jennifer E., Coloff, Jonathan L., Selfors, Laura M., McBrayer, Samuel K., Rosenbluth, Jennifer M., Takahashi, Nobuaki, Dhakal, Sabin, Koduri, Vidyasagar, Oser, Matthew G., Schauer, Nathan J., Doherty, Laura M., Hong, Andrew L., Kang, Yun Pyo, Younger, Scott T., Doench, John G., Hahn, William C., Buhrlage, Sara J., DeNicola, Gina M., Kaelin, William G., Brugge, Joan S.
Published in Cell Metab (2019)

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

by Dempster, Joshua M., Pacini, Clare, Pantel, Sasha, Behan, Fiona M., Green, Thomas, Krill-Burger, John, Beaver, Charlotte M., Younger, Scott T., Zhivich, Victor, Najgebauer, Hanna, Allen, Felicity, Gonçalves, Emanuel, Shepherd, Rebecca, Doench, John G., Yusa, Kosuke, Vazquez, Francisca, Parts, Leopold, Boehm, Jesse S., Golub, Todd R., Hahn, William C., Root, David E., Garnett, Mathew J., Tsherniak, Aviad, Iorio, Francesco
Published in Nat Commun (2019)

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

by Marinaccio, Christian, Suraneni, Praveen, Celik, Hamza, Volk, Andrew, Wen, Qiang Jeremy, Ling, Te, Bulic, Marinka, Lasho, Terra, Koche, Richard P., Famulare, Christopher A., Farnoud, Noushin, Stein, Brady, Schieber, Michael, Gurbuxani, Sandeep, Root, David E., Younger, Scott T., Hoffman, Ronald, Gangat, Naseema, Ntziachristos, Panagiotis, Chandel, Navdeep S., Levine, Ross L, Rampal, Raajit K., Challen, Grant A., Tefferi, Ayalew, Crispino, John D.
Published in Cancer Discov (2021)