The Puzzle of RNAs that Target Gene Promoters

gan Younger, Scott T., Corey, David R.
Cyhoeddwyd 2009

Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

gan Younger, Scott T., Corey, David R.
Cyhoeddwyd 2011

'Lnc'-ing enhancers to MYC regulation

gan Younger, Scott T, Rinn, John L
Cyhoeddwyd 2014

Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini()

gan Younger, Scott T., Corey, David R.
Cyhoeddwyd yn Mol Biosyst (2011)

Silent pericentromeric repeats speak out

gan Younger, Scott T., Rinn, John L.
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2015)

p53 regulates enhancer accessibility and activity in response to DNA damage

gan Younger, Scott T., Rinn, John L.
Cyhoeddwyd yn Nucleic Acids Res (2017)

Identification of functional regulatory elements in the human genome using pooled CRISPR screens

gan Borys, Samantha M., Younger, Scott T.
Cyhoeddwyd yn BMC Genomics (2020)

Predicting potential miRNA target sites within gene promoters

gan Younger, Scott T., Pertsemlidis, Alexander, Corey, David R.
Cyhoeddwyd 2009

CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo

gan Shechner, David M., Hacisüleyman, Ezgi, Younger, Scott T., Rinn, John L.
Cyhoeddwyd yn Nat Methods (2015)

Expediting rare disease diagnosis: a call to bridge the gap between clinical and functional genomics

gan Hartin, Samantha N., Means, John C., Alaimo, Joseph T., Younger, Scott T.
Cyhoeddwyd yn Mol Med (2020)

FOXC2 Autoregulates Its Expression in the Pulmonary Endothelium After Endotoxin Stimulation in a Histone Acetylation-Dependent Manner

gan Xia, Sheng, Yu, Wei, Menden, Heather, Younger, Scott T., Sampath, Venkatesh
Cyhoeddwyd yn Front Cell Dev Biol (2021)

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

gan Chu, Yongjun, Yue, Xuan, Younger, Scott T., Janowski, Bethany A., Corey, David R.
Cyhoeddwyd 2010

Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage

gan Younger, Scott T., Kenzelmann-Broz, Daniela, Jung, Heiyoun, Attardi, Laura D., Rinn, John L.
Cyhoeddwyd yn Nucleic Acids Res (2015)

Regulation of Transcription by Small RNAs Complementary to Sequences Downstream from the 3’ Termini of Genes

gan Yue, Xuan, Schwartz, Jacob C., Younger, Scott T., Chu, Yongjun, Gagnon, Keith T., Elbashir, Sayda, Janowski, Bethany A., Corey, David R.
Cyhoeddwyd 2010

Antisense transcripts are targets for activating small RNAs

gan Schwartz, Jacob C, Younger, Scott T, Nguyen, Ngoc-Bich, Hardy, Daniel B, Monia, Brett P, Corey, David R, Janowski, Bethany A
Cyhoeddwyd 2008

Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction

gan Younger, Scott, Jang, Hyunbum, Davies, Hannah A., Niemiec, Martin J., Garcia, Joe G.N., Nussinov, Ruth, Migrino, Raymond Q., Madine, Jillian, Arce, Fernando T.
Cyhoeddwyd yn Biophys J (2020)

Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens

gan Najm, Fadi J, Strand, Christine, Donovan, Katherine F, Hegde, Mudra, Sanson, Kendall R, Vaimberg, Emma W, Sullender, Meagan E, Hartenian, Ella, Kalani, Zohra, Fusi, Nicolo, Listgarten, Jennifer, Younger, Scott T, Bernstein, Bradley E, Root, David E, Doench, John G
Cyhoeddwyd yn Nat Biotechnol (2017)

Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion

gan Harris, Isaac S., Endress, Jennifer E., Coloff, Jonathan L., Selfors, Laura M., McBrayer, Samuel K., Rosenbluth, Jennifer M., Takahashi, Nobuaki, Dhakal, Sabin, Koduri, Vidyasagar, Oser, Matthew G., Schauer, Nathan J., Doherty, Laura M., Hong, Andrew L., Kang, Yun Pyo, Younger, Scott T., Doench, John G., Hahn, William C., Buhrlage, Sara J., DeNicola, Gina M., Kaelin, William G., Brugge, Joan S.
Cyhoeddwyd yn Cell Metab (2019)

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

gan Dempster, Joshua M., Pacini, Clare, Pantel, Sasha, Behan, Fiona M., Green, Thomas, Krill-Burger, John, Beaver, Charlotte M., Younger, Scott T., Zhivich, Victor, Najgebauer, Hanna, Allen, Felicity, Gonçalves, Emanuel, Shepherd, Rebecca, Doench, John G., Yusa, Kosuke, Vazquez, Francisca, Parts, Leopold, Boehm, Jesse S., Golub, Todd R., Hahn, William C., Root, David E., Garnett, Mathew J., Tsherniak, Aviad, Iorio, Francesco
Cyhoeddwyd yn Nat Commun (2019)

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

gan Marinaccio, Christian, Suraneni, Praveen, Celik, Hamza, Volk, Andrew, Wen, Qiang Jeremy, Ling, Te, Bulic, Marinka, Lasho, Terra, Koche, Richard P., Famulare, Christopher A., Farnoud, Noushin, Stein, Brady, Schieber, Michael, Gurbuxani, Sandeep, Root, David E., Younger, Scott T., Hoffman, Ronald, Gangat, Naseema, Ntziachristos, Panagiotis, Chandel, Navdeep S., Levine, Ross L, Rampal, Raajit K., Challen, Grant A., Tefferi, Ayalew, Crispino, John D.
Cyhoeddwyd yn Cancer Discov (2021)