Mapping SOD1 domains of non-native interaction: Roles of intra-and inter-molecular disulfide bonding in aggregation

per Wang, Jiou, Xu, Guilian, Borchelt, David R.
Publicat 2006

Lactic Acid Induces Aberrant Amyloid Precursor Protein Processing by Promoting Its Interaction with Endoplasmic Reticulum Chaperone Proteins

per Xiang, Yiwen, Xu, Guilian, Weigel-Van Aken, Kirsten A. K.
Publicat 2010

Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9...

per Xu, Guilian, Green, Cameron C, Fromholt, Susan E, Borchelt, David R
Publicat 2012

Alzheimer's-Type Amyloidosis in Transgenic Mice Impairs Survival of Newborn Neurons Derived from Adult Hippocampal Neurogenesis

per Verret, Laure, Jankowsky, Joanna L., Xu, Guilian M., Borchelt, David R., Rampon, Claire
Publicat a J Neurosci (2007)

Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis

per Xu, Guilian, Stevens, Stanley M., Moore, Brenda D., McClung, Scott, Borchelt, David R.
Publicat 2013

Vulnerability of newly synthesized proteins to proteostasis stress

per Xu, Guilian, Pattamatta, Amrutha, Hildago, Ryan, Pace, Michael C., Brown, Hilda, Borchelt, David R.
Publicat a J Cell Sci (2016)

Long-term efficacy of different procedures for treatment of varicose veins: A network meta-analysis

per Guo, Liqin, Huang, Rong, Zhao, Dunyong, Xu, Guilian, Liu, Hui, Yang, Jian, Guo, Tao
Publicat a Medicine (Baltimore) (2019)

Receptor-Associated Protein (RAP) Plays a Central Role in Modulating Aβ Deposition in APP/PS1 Transgenic Mice

per Xu, Guilian, Karch, Celeste, Li, Ning, Lin, Nianwei, Fromholt, David, Gonzales, Victoria, Borchelt, David R.
Publicat 2008

Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases

per Ayers, Jacob I, Xu, Guilian, Pletnikova, Olga, Troncoso, Juan C, Hart, P John, Borchelt, David R
Publicat 2014

Identification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines

per Xu, Guilian, Stevens, Stanley M., Kobiessy, Firas, Brown, Hilda, McClung, Scott, Gold, Mark S., Borchelt, David R.
Publicat 2012

Correction: Identification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines

per Xu, Guilian, Stevens, Stanley M., Kobiessy, Firas, Brown, Hilda, McClung, Scott, Gold, Mark S., Borchelt, David R.
Publicat 2012

Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice

per Xu, Guilian, Ayers, Jacob I., Roberts, Brittany L., Brown, Hilda, Fromholt, Susan, Green, Cameron, Borchelt, David R.
Publicat a Hum Mol Genet (2015)

Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits

per Xu, Guilian, Ran, Yong, Fromholt, Susan E., Fu, Chunhua, Yachnis, Anthony T., Golde, Todd E., Borchelt, David R.
Publicat a Acta Neuropathol Commun (2015)

Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology

per Pace, Michael C., Xu, Guilian, Fromholt, Susan, Howard, John, Giasson, Benoit I., Lewis, Jada, Borchelt, David R.
Publicat a Mol Neurodegener (2018)

Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease

per Pace, Michael C., Xu, Guilian, Fromholt, Susan, Howard, John, Crosby, Keith, Giasson, Benoit I., Lewis, Jada, Borchelt, David R.
Publicat a Acta Neuropathol (2018)

Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation

per Xu, Guilian, Fromholt, Susan, Ayers, Jacob I., Brown, Hilda, Siemienski, Zoe, Crosby, Keith W., Mayer, Christopher A., Janus, Christopher, Borchelt, David R.
Publicat a J Neurochem (2015)

Amyloid precursor protein increases cortical neuron size in transgenic mice

per Oh, Esther S., Savonenko, Alena V., King, Julie F., Fangmark Tucker, Stina M., Rudow, Gay L., Xu, Guilian, Borchelt, David R., Troncoso, Juan C.
Publicat 2008

Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence

per Ayers, Jacob I., Xu, Guilian, Dillon, Kristy, Lu, Qing, Chen, Zhijuan, Beckman, John, Moreno-Romero, Alma K., Zamora, Diana L., Galaleldeen, Ahmad, Borchelt, David R.
Publicat a Acta Neuropathol Commun (2021)

Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis

per Xu, Guilian, Fromholt, Susan E., Chakrabarty, Paramita, Zhu, Fanchao, Liu, Xuefei, Pace, Michael C., Koh, Jin, Golde, Todd E., Levites, Yona, Lewis, Jada, Borchelt, David R.
Publicat a Acta Neuropathol Commun (2020)

Reversible Pathologic and Cognitive Phenotypes in an Inducible Model of Alzheimer-Amyloidosis

per Melnikova, Tatiana, Fromholt, Susan, Kim, HyunSu, Lee, Deidre, Xu, Guilian, Price, Ashleigh, Moore, Brenda D., Golde, Todd E., Felsenstein, Kevin M., Savonenko, Alena, Borchelt, David R.
Publicat 2013