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Vulnerability of newly synthesized proteins to proteostasis stress
The capacity of the cell to produce, fold and degrade proteins relies on components of the proteostasis network. Multiple types of insults can impose a burden on this network, causing protein misfolding. Using thermal stress, a classic example of acute proteostatic stress, we demonstrate that ∼5–10%...
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| Publicado no: | J Cell Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4893652/ https://ncbi.nlm.nih.gov/pubmed/27026526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.176479 |
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