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Amyloid precursor protein increases cortical neuron size in transgenic mice

The amyloid precursor protein (APP) is the source of β-amyloid, a pivotal peptide in the pathogenesis of Alzheimer’s disease (AD). This study examines the possible effect of APP transgene expression on neuronal size by measuring the volumes of cortical neurons (μm(3)) in transgenic mouse models with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Oh, Esther S., Savonenko, Alena V., King, Julie F., Fangmark Tucker, Stina M., Rudow, Gay L., Xu, Guilian, Borchelt, David R., Troncoso, Juan C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796369/
https://ncbi.nlm.nih.gov/pubmed/18304698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.12.024
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