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Amyloid-Associated Neuron Loss and Gliogenesis in the Neocortex of Amyloid Precursor Protein Transgenic Mice

APP23 transgenic mice express mutant human amyloid precursor protein and develop amyloid plaques predominantly in neocortex and hippocampus progressively with age, similar to Alzheimer's disease. We have previously reported neuron loss in the hippocampal CA1 region of 14- to 18-month-old APP23...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bondolfi, Luca, Calhoun, Michael, Ermini, Florian, Kuhn, H. Georg, Wiederhold, Karl-Heinz, Walker, Lary, Staufenbiel, Matthias, Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758656/
https://ncbi.nlm.nih.gov/pubmed/11784797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-02-00515.2002
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