Amyloid-Associated Neuron Loss and Gliogenesis in the Neocortex of Amyloid Precursor Protein Transgenic Mice

APP23 transgenic mice express mutant human amyloid precursor protein and develop amyloid plaques predominantly in neocortex and hippocampus progressively with age, similar to Alzheimer's disease. We have previously reported neuron loss in the hippocampal CA1 region of 14- to 18-month-old APP23...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Bondolfi, Luca, Calhoun, Michael, Ermini, Florian, Kuhn, H. Georg, Wiederhold, Karl-Heinz, Walker, Lary, Staufenbiel, Matthias, Jucker, Mathias
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2002
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ARTICLE
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758656/
https://ncbi.nlm.nih.gov/pubmed/11784797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-02-00515.2002
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