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Cerebral Amyloid Induces Aberrant Axonal Sprouting and Ectopic Terminal Formation in Amyloid Precursor Protein Transgenic Mice

A characteristic feature of Alzheimer’s disease (AD) is the formation of amyloid plaques in the brain. Although this hallmark pathology has been well described, the biological effects of plaques are poorly understood. To study the effect of amyloid plaques on axons and neuronal connectivity, we have...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Phinney, Amie L., Deller, Thomas, Stalder, Martina, Calhoun, Michael E., Frotscher, Michael, Sommer, Bernd, Staufenbiel, Matthias, Jucker, Mathias
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783025/
https://ncbi.nlm.nih.gov/pubmed/10493755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08552.1999
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