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Cerebral Amyloid Induces Aberrant Axonal Sprouting and Ectopic Terminal Formation in Amyloid Precursor Protein Transgenic Mice

A characteristic feature of Alzheimer’s disease (AD) is the formation of amyloid plaques in the brain. Although this hallmark pathology has been well described, the biological effects of plaques are poorly understood. To study the effect of amyloid plaques on axons and neuronal connectivity, we have...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Phinney, Amie L., Deller, Thomas, Stalder, Martina, Calhoun, Michael E., Frotscher, Michael, Sommer, Bernd, Staufenbiel, Matthias, Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783025/
https://ncbi.nlm.nih.gov/pubmed/10493755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08552.1999
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