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Cerebral Amyloid Induces Aberrant Axonal Sprouting and Ectopic Terminal Formation in Amyloid Precursor Protein Transgenic Mice

A characteristic feature of Alzheimer’s disease (AD) is the formation of amyloid plaques in the brain. Although this hallmark pathology has been well described, the biological effects of plaques are poorly understood. To study the effect of amyloid plaques on axons and neuronal connectivity, we have...

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Publicat a:J Neurosci
Autors principals: Phinney, Amie L., Deller, Thomas, Stalder, Martina, Calhoun, Michael E., Frotscher, Michael, Sommer, Bernd, Staufenbiel, Matthias, Jucker, Mathias
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783025/
https://ncbi.nlm.nih.gov/pubmed/10493755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08552.1999
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