Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy

A high risk factor for spontaneous and often fatal lobar hemorrhage is cerebral amyloid angiopathy (CAA). We now report that CAA in an amyloid precursor protein transgenic mouse model (APP23 mice) leads to a loss of vascular smooth muscle cells, aneurysmal vasodilatation, and in rare cases, vessel o...

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Vydáno v:J Neurosci
Hlavní autoři: Winkler, David T., Bondolfi, Luca, Herzig, Martin C., Jann, Lukas, Calhoun, Michael E., Wiederhold, Karl-Heinz, Tolnay, Markus, Staufenbiel, Matthias, Jucker, Mathias
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762950/
https://ncbi.nlm.nih.gov/pubmed/11222652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-05-01619.2001
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