Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy

A high risk factor for spontaneous and often fatal lobar hemorrhage is cerebral amyloid angiopathy (CAA). We now report that CAA in an amyloid precursor protein transgenic mouse model (APP23 mice) leads to a loss of vascular smooth muscle cells, aneurysmal vasodilatation, and in rare cases, vessel o...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Winkler, David T., Bondolfi, Luca, Herzig, Martin C., Jann, Lukas, Calhoun, Michael E., Wiederhold, Karl-Heinz, Tolnay, Markus, Staufenbiel, Matthias, Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762950/
https://ncbi.nlm.nih.gov/pubmed/11222652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-05-01619.2001
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