Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

Amyloid precursor protein (APP) and its cleavage product amyloid β (Aβ) have been thoroughly studied in Alzheimer’s disease. However, APP also appears to be important for neuronal development. Differentiation of induced pluripotent stem cells (iPSCs) towards cortical neurons enables in vitro mechani...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Bergström, Petra, Agholme, Lotta, Nazir, Faisal Hayat, Satir, Tugce Munise, Toombs, Jamie, Wellington, Henrietta, Strandberg, Joakim, Bontell, Thomas Olsson, Kvartsberg, Hlin, Holmström, Maria, Boreström, Cecilia, Simonsson, Stina, Kunath, Tilo, Lindahl, Anders, Blennow, Kaj, Hanse, Eric, Portelius, Erik, Wray, Selina, Zetterberg, Henrik
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935877/
https://ncbi.nlm.nih.gov/pubmed/27383650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29200
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires