Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

Amyloid precursor protein (APP) and its cleavage product amyloid β (Aβ) have been thoroughly studied in Alzheimer’s disease. However, APP also appears to be important for neuronal development. Differentiation of induced pluripotent stem cells (iPSCs) towards cortical neurons enables in vitro mechani...

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書誌詳細
出版年:Sci Rep
主要な著者: Bergström, Petra, Agholme, Lotta, Nazir, Faisal Hayat, Satir, Tugce Munise, Toombs, Jamie, Wellington, Henrietta, Strandberg, Joakim, Bontell, Thomas Olsson, Kvartsberg, Hlin, Holmström, Maria, Boreström, Cecilia, Simonsson, Stina, Kunath, Tilo, Lindahl, Anders, Blennow, Kaj, Hanse, Eric, Portelius, Erik, Wray, Selina, Zetterberg, Henrik
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935877/
https://ncbi.nlm.nih.gov/pubmed/27383650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29200
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