Partial reduction of amyloid β production by β-secretase inhibitors does not decrease synaptic transmission

BACKGROUND: Alzheimer’s disease (AD) is the most common form of age-related neurodegenerative diseases. Cerebral deposition of Aβ peptides, especially Aβ42, is considered the major neuropathological hallmark of AD and the putative cause of AD-related neurotoxicity. Aβ peptides are produced by sequen...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Alzheimers Res Ther
Auteurs principaux: Satir, Tugce Munise, Agholme, Lotta, Karlsson, Anna, Karlsson, Mattias, Karila, Paul, Illes, Sebastian, Bergström, Petra, Zetterberg, Henrik
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251689/
https://ncbi.nlm.nih.gov/pubmed/32456694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00635-0
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires