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Partial reduction of amyloid β production by β-secretase inhibitors does not decrease synaptic transmission
BACKGROUND: Alzheimer’s disease (AD) is the most common form of age-related neurodegenerative diseases. Cerebral deposition of Aβ peptides, especially Aβ42, is considered the major neuropathological hallmark of AD and the putative cause of AD-related neurotoxicity. Aβ peptides are produced by sequen...
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| Publicat a: | Alzheimers Res Ther |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7251689/ https://ncbi.nlm.nih.gov/pubmed/32456694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00635-0 |
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