A carregar...

Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons

One of the neuropathological hallmarks of Alzheimer’s disease (AD) is cerebral deposition of amyloid plaques composed of amyloid β (Aβ) peptides and the cerebrospinal fluid concentrations of those peptides are used as a biomarker for AD. Mature induced pluripotent stem cell (iPSC)-derived cortical n...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Satir, Tugce Munise, Nazir, Faisal Hayat, Vizlin-Hodzic, Dzeneta, Hardselius, Erik, Blennow, Kaj, Wray, Selina, Zetterberg, Henrik, Agholme, Lotta, Bergström, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969066/
https://ncbi.nlm.nih.gov/pubmed/31953468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57516-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!