Maize Photosystem I : Identification of the Subunit which Binds Plastocyanin

Por Wynn, R. Max, Luong, Christine, Malkin, Richard
Publicado em 1989

Subunit and Catalytic Component Stoichiometries of an in Vitro Reconstituted Human Pyruvate Dehydrogenase Complex

Por Brautigam, Chad A., Wynn, R. Max, Chuang, Jacinta L., Chuang, David T.
Publicado em 2009

GM130 regulates Golgi-derived spindle assembly by activating TPX2 and capturing microtubules

Por Wei, Jen-Hsuan, Zhang, Zi Chao, Wynn, R. Max, Seemann, Joachim
Publicado no Cell (2015)

Structure of rat BCKD kinase: Nucleotide-induced domain communication in a mitochondrial protein kinase

Por Machius, Mischa, Chuang, Jacinta L., Wynn, R. Max, Tomchick, Diana R., Chuang, David T.
Publicado em 2001

Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex

Por Kato, Masato, Chuang, Jacinta L, Tso, Shih-Chia, Wynn, R Max, Chuang, David T
Publicado em 2005

Structural and Biochemical Characterization of Human Mitochondrial Branched-chain α-Ketoacid Dehydrogenase Phosphatase

Por Wynn, R. Max, Li, Jun, Brautigam, Chad A., Chuang, Jacinta L., Chuang, David T.
Publicado em 2012

Metabolite Regulation of Nucleo-cytosolic Trafficking of Carbohydrate Response Element-binding Protein (ChREBP): ROLE OF KETONE BODIES

Por Nakagawa, Tsutomu, Ge, Qiang, Pawlosky, Robert, Wynn, R. Max, Veech, Richard L., Uyeda, Kosaku
Publicado em 2013

A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain α-ketoacid dehydrogenase complex

Por Kato, Masato, Wynn, R Max, Chuang, Jacinta L, Brautigam, Chad A, Custorio, Myra, Chuang, David T
Publicado em 2006

Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity

Por Wynn, R. Max, Kato, Masato, Chuang, Jacinta L., Tso, Shih-Chia, Li, Jun, Chuang, David T.
Publicado em 2008

Importin-α Protein Binding to a Nuclear Localization Signal of Carbohydrate Response Element-Binding Protein (ChREBP)

Por Ge, Qiang, Nakagawa, Tsutomu, Wynn, R. Max, Chook, Yuh Min, Miller, Bonnie C., Uyeda, Kosaku
Publicado em 2011

Branched-chain Amino Acid Metabolon: INTERACTION OF GLUTAMATE DEHYDROGENASE WITH THE MITOCHONDRIAL BRANCHED-CHAIN AMINOTRANSFERASE (BCATm)

Por Islam, Mohammad Mainul, Nautiyal, Manisha, Wynn, R. Max, Mobley, James A., Chuang, David T., Hutson, Susan M.
Publicado em 2010

Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3-binding protein of human pyruvate dehydrogenase complex

Por Brautigam, Chad A., Wynn, R. Max, Chuang, Jacinta L., Machius, Mischa, Tomchick, Diana R., Chuang, David T.
Publicado em 2006

Maple Syrup Urine Disease in Cypriot Families: Identification of Three Novel Mutations and Biochemical Characterization of the p.Thr211Met Mutation in the E1α Subunit

Por Georgiou, Theodoros, Chuang, Jacinta L., Wynn, R. Max, Stylianidou, Goula, Korson, Mark, Chuang, David T., Drousiotou, Anthi
Publicado em 2009

Structural Characterization of a Unique Interface between Carbohydrate Response Element-binding Protein (ChREBP) and 14-3-3β Protein

Por Ge, Qiang, Huang, Nian, Wynn, R. Max, Li, Yang, Du, Xinlin, Miller, Bonnie, Zhang, Hong, Uyeda, Kosaku
Publicado em 2012

Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain α-Ketoacid Dehydrogenase Complex

Por Brautigam, Chad A., Wynn, R. Max, Chuang, Jacinta L., Naik, Mandar T., Young, Brittany B., Huang, Tai-huang, Chuang, David T.
Publicado em 2011

Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP): INTERACTION OF AN α-HELIX OF ChREBP WITH THE 14-3-3 PROTEINS AND REGULATION BY PHO...

Por Sakiyama, Haruhiko, Wynn, R. Max, Lee, Wan-Ru, Fukasawa, Masashi, Mizuguchi, Hiroyuki, Gardner, Kevin H., Repa, Joyce J., Uyeda, Kosaku
Publicado em 2008

Determination of Protein Complex Stoichiometry Through Multisignal Sedimentation Velocity Experiments

Por Padrick, Shae B., Deka, Ranjit K., Chuang, Jacinta L., Wynn, R. Max, Chuang, David T., Norgard, Michael V., Rosen, Michael K., Brautigam, Chad A.
Publicado em 2010

Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice

Por Wu, Cheng-Yang, Tso, Shih-Chia, Chuang, Jacinta L., Gui, Wen-Jun, Lou, Mingliang, Sharma, Gaurav, Khemtong, Chalermchai, Qi, Xiangbing, Wynn, R. Max, Chuang, David T.
Publicado no Mol Metab (2018)

Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-targeting Pyruvate Dehydrogenase Kinase Inhibitors

Por Tso, Shih-Chia, Lou, Mingliang, Wu, Cheng-Yang, Gui, Wen-Jun, Chuang, Jacinta L., Morlock, Lorraine K., Williams, Noelle S., Wynn, R. Max, Qi, Xiangbing, Chuang, David T.
Publicado no J Med Chem (2017)

A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity

Por Wu, Cheng-Yang, Satapati, Santhosh, Gui, Wenjun, Wynn, R. Max, Sharma, Gaurav, Lou, Mingliang, Qi, Xiangbing, Burgess, Shawn C., Malloy, Craig, Khemtong, Chalermchai, Sherry, A. Dean, Chuang, David T., Merritt, Matthew E.
Publicado no J Biol Chem (2018)