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Structural and Biochemical Characterization of Human Mitochondrial Branched-chain α-Ketoacid Dehydrogenase Phosphatase

The branched-chain α-ketoacid dehydrogenase phosphatase (BDP) component of the human branched-chain α-ketoacid dehydrogenase complex (BCKDC) has been expressed in Escherichia coli and purified in the soluble form. The monomeric BDP shows a strict dependence on Mn(2+) ions for phosphatase activity, w...

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Detalhes bibliográficos
Main Authors: Wynn, R. Max, Li, Jun, Brautigam, Chad A., Chuang, Jacinta L., Chuang, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308798/
https://ncbi.nlm.nih.gov/pubmed/22291014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314963
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