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Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3-binding protein of human pyruvate dehydrogenase complex

The 9.5-megadalton human pyruvate dehydrogenase complex (PDC) utilizes the specific dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) to tether the essential E3 component to the 60-meric core of the complex. Here, we report crystal structures of the binding domain (E3BD) of human E3BP alone...

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Detalhes bibliográficos
Main Authors: Brautigam, Chad A., Wynn, R. Max, Chuang, Jacinta L., Machius, Mischa, Tomchick, Diana R., Chuang, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879633/
https://ncbi.nlm.nih.gov/pubmed/16442803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2006.01.001
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