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Subunit and Catalytic Component Stoichiometries of an in Vitro Reconstituted Human Pyruvate Dehydrogenase Complex

The human pyruvate dehydrogenase complex (PDC) is a 9.5-megadalton catalytic machine that employs three catalytic components, i.e. pyruvate dehydrogenase (E1p), dihydrolipoyl transacetylase (E2p), and dihydrolipoamide dehydrogenase (E3), to carry out the oxidative decarboxylation of pyruvate. The hu...

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Bibliografiska uppgifter
Huvudupphovsmän: Brautigam, Chad A., Wynn, R. Max, Chuang, Jacinta L., Chuang, David T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676041/
https://ncbi.nlm.nih.gov/pubmed/19240034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806563200
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