Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP): INTERACTION OF AN α-HELIX OF ChREBP WITH THE 14-3-3 PROTEINS AND REGULATION BY PHOSPHORYLATION

Carbohydrate response element-binding protein (ChREBP) is a glucose-responsive transcription factor that plays a critical role in the glucose-mediated induction of gene products involved in hepatic glycolysis and lipogenesis. Glucose affects the activity of ChREBP largely through post-translational...

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Detalhes bibliográficos
Main Authors: Sakiyama, Haruhiko, Wynn, R. Max, Lee, Wan-Ru, Fukasawa, Masashi, Mizuguchi, Hiroyuki, Gardner, Kevin H., Repa, Joyce J., Uyeda, Kosaku
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259841/
https://ncbi.nlm.nih.gov/pubmed/18606808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804308200
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