Metabolite Regulation of Nucleo-cytosolic Trafficking of Carbohydrate Response Element-binding Protein (ChREBP): ROLE OF KETONE BODIES

The carbohydrate response element-binding protein (ChREBP) is a glucose-responsive transcription factor that plays a critical role in converting excess carbohydrate to storage fat in liver. In response to changing glucose levels, ChREBP activity is regulated by nucleo-cytoplasmic shuttling of ChREBP...

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Bibliographic Details
Main Authors: Nakagawa, Tsutomu, Ge, Qiang, Pawlosky, Robert, Wynn, R. Max, Veech, Richard L., Uyeda, Kosaku
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784753/
https://ncbi.nlm.nih.gov/pubmed/23918932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498550
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