Mapping the pathways of resistance to targeted therapies

Por Wood, Kris C.
Publicado no Cancer Res (2015)

Growth signaling at the nexus of stem cell life and death

Por Wood, Kris C., Sabatini, David M.
Publicado em 2009

Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes

Por Singleton, Katherine R., Wood, Kris C.
Publicado no Genes Cancer (2016)

Controlling interlayer diffusion to achieve sustained, multiagent delivery from layer-by-layer thin films

Por Wood, Kris C., Chuang, Helen F., Batten, Robert D., Lynn, David M., Hammond, Paula T.
Publicado em 2006

Electroactive controlled release thin films

Por Wood, Kris C., Zacharia, Nicole S., Schmidt, Daniel J., Wrightman, Stefani N., Andaya, Brian J., Hammond, Paula T.
Publicado em 2008

RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis

Por Winter, Peter S., Sarosiek, Kristopher A., Lin, Kevin H., Meggendorfer, Manja, Schnittger, Susanne, Letai, Anthony, Wood, Kris C.
Publicado no Sci Signal (2014)

Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance

Por Ali, Moiez, Kaltenbrun, Erin, Anderson, Gray R., Stephens, Sarah Jo, Arena, Sabrina, Bardelli, Alberto, Counter, Christopher M., Wood, Kris C.
Publicado no Nat Commun (2017)

Targeting MCL-1/BCL-X(L) Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia

Por Lin, Kevin H., Winter, Peter S., Xie, Abigail, Roth, Cullen, Martz, Colin A., Stein, Elizabeth M., Anderson, Gray R., Tingley, Jennifer P., Wood, Kris C.
Publicado no Sci Rep (2016)

Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors

Por Anderson, Gray R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.
Publicado no Nat Commun (2018)

MicroSCALE Screening Reveals Genetic Modifiers of Therapeutic Response in Melanoma

Por Wood, Kris C., Konieczkowski, David J., Johannessen, Cory M., Boehm, Jesse S., Tamayo, Pablo, Botvinnik, Olga B., Mesirov, Jill P., Hahn, William C., Root, David E., Garraway, Levi A., Sabatini, David M.
Publicado em 2012

ERRα Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer

Por Park, Sunghee, Chang, Ching-yi, Safi, Rachid, Liu, Xiaojing, Baldi, Robert, Jasper, Jeff S., Anderson, Grace R., Liu, Tingyu, Rathmell, Jeffrey C., Dewhirst, Mark W., Wood, Kris C., Locasale, Jason W., McDonnell, Donald P.
Publicado no Cell Rep (2016)

Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers

Por Misale, Sandra, Bozic, Ivana, Tong, Jingshan, Peraza-Penton, Ashley, Lallo, Alice, Baldi, Federica, Lin, Kevin H., Truini, Mauro, Trusolino, Livio, Bertotti, Andrea, Di Nicolantonio, Federica, Nowak, Martin A., Zhang, Lin, Wood, Kris C., Bardelli, Alberto
Publicado no Nat Commun (2015)

Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection

Por Price, Alexander M, Dai, Joanne, Bazot, Quentin, Patel, Luv, Nikitin, Pavel A, Djavadian, Reza, Winter, Peter S, Salinas, Cristina A, Barry, Ashley Perkins, Wood, Kris C, Johannsen, Eric C, Letai, Anthony, Allday, Martin J, Luftig, Micah A
Publicado no eLife (2017)

An Automated High-throughput Array Microscope for Cancer Cell Mechanics

Por Cribb, Jeremy A., Osborne, Lukas D., Beicker, Kellie, Psioda, Matthew, Chen, Jian, O’Brien, E. Timothy, Taylor II, Russell M., Vicci, Leandra, Hsiao, Joe Ping-Lin, Shao, Chong, Falvo, Michael, Ibrahim, Joseph G., Wood, Kris C., Blobe, Gerard C., Superfine, Richard
Publicado no Sci Rep (2016)

PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation

Por Anderson, Grace R., Wardell, Suzanne E., Cakir, Merve, Crawford, Lorin, Leeds, Jim C., Nussbaum, Daniel P., Shankar, Pallavi S., Soderquist, Ryan S., Stein, Elizabeth M., Tingley, Jennifer P., Winter, Peter S., Zieser-Misenheimer, Elizabeth K., Alley, Holly M., Yllanes, Alexander, Haney, Victoria, Blackwell, Kimberly L., McCall, Shannon J., McDonnell, Donald P., Wood, Kris C.
Publicado no Sci Transl Med (2016)

Systematic identification of signaling pathways with potential to confer anticancer drug resistance

Por Martz, Colin A., Ottina, Kathleen A., Singleton, Katherine R., Jasper, Jeff S., Wardell, Suzanne E., Peraza-Penton, Ashley, Anderson, Grace R., Winter, Peter S., Wang, Tim, Alley, Holly M., Kwong, Lawrence N., Cooper, Zachary A., Tetzlaff, Michael, Chen, Pei-Ling, Rathmell, Jeffrey C., Flaherty, Keith T., Wargo, Jennifer A., McDonnell, Donald P., Sabatini, David M., Wood, Kris C.
Publicado no Sci Signal (2014)

A landscape of therapeutic cooperativity in KRAS mutant cancers reveals principles for controlling tumor evolution

Por Anderson, Grace R., Winter, Peter S., Lin, Kevin H., Nussbaum, Daniel P., Cakir, Merve, Stein, Elizabeth M., Soderquist, Ryan S., Crawford, Lorin, Leeds, Jim C., Newcomb, Rachel, Stepp, Priya, Yip, Catherine, Wardell, Suzanne E., Tingley, Jennifer P., Ali, Moiez, Xu, Mengmeng, Ryan, Meagan, McCall, Shannon J., McRee, Autumn J., Counter, Christopher M., Der, Channing J., Wood, Kris C.
Publicado no Cell Rep (2017)

Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence

Por Singleton, Katherine R., Crawford, Lorin, Tsui, Elizabeth, Manchester, Haley E., Maertens, Ophelia, Liu, Xiaojing, Liberti, Maria V., Magpusao, Anniefer N., Stein, Elizabeth M., Tingley, Jennifer P., Frederick, Dennie T., Boland, Genevieve M., Flaherty, Keith T., McCall, Shannon J., Krepler, Clemens, Sproesser, Katrin, Herlyn, Meenhard, Adams, Drew J., Locasale, Jason W., Cichowski, Karen, Mukherjee, Sayan, Wood, Kris C.
Publicado no Cell Rep (2017)

Metabolic programming and PDHK1 control CD4(+) T cell subsets and inflammation

Por Gerriets, Valerie A., Kishton, Rigel J., Nichols, Amanda G., Macintyre, Andrew N., Inoue, Makoto, Ilkayeva, Olga, Winter, Peter S., Liu, Xiaojing, Priyadharshini, Bhavana, Slawinska, Marta E., Haeberli, Lea, Huck, Catherine, Turka, Laurence A., Wood, Kris C., Hale, Laura P., Smith, Paul A., Schneider, Martin A., MacIver, Nancie J., Locasale, Jason W., Newgard, Christopher B., Shinohara, Mari L., Rathmell, Jeffrey C.
Publicado no J Clin Invest (2014)