Akt-Dependent Glucose Metabolism Promotes Mcl-1 Synthesis to Maintain Cell Survival and Resistance to Bcl-2 Inhibition

Por Coloff, Jonathan L., Macintyre, Andrew N., Nichols, Amanda G., Liu, Tingyu, Gallo, Catherine A., Plas, David R., Rathmell, Jeffrey C.
Publicado em 2011

Leptin Directly Promotes T Cell Glycolytic Metabolism to Drive Effector T cell Differentiation in Autoimmunity

Por Gerriets, Valerie A., Danzaki, Keiko, Kishton, Rigel J., Eisner, William, Nichols, Amanda G., Saucillo, Donte C., Shinohara, Mari L., MacIver, Nancie J.
Publicado no Eur J Immunol (2016)

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4(+) T Cell Subsets

Por Michalek, Ryan D., Gerriets, Valerie A., Jacobs, Sarah R., Macintyre, Andrew N., MacIver, Nancie J., Mason, Emily F., Sullivan, Sarah A., Nichols, Amanda G., Rathmell, Jeffrey C.
Publicado em 2011

Metabolic Reprogramming is Required for Antibody Production That is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B cells

Por Caro-Maldonado, Alfredo, Wang, Ruoning, Nichols, Amanda G., Kuraoka, Masayuki, Milasta, Sandra, Sun, Lillian D., Gavin, Amanda L., Abel, E. Dale, Kelsoe, Garnett, Green, Douglas R., Rathmell, Jeffrey C.
Publicado em 2014

The Glucose Transporter Glut1 is Selectively Essential for CD4 T Cell Activation and Effector Function

Por Macintyre, Andrew N., Gerriets, Valerie A., Nichols, Amanda G., Michalek, Ryan D., Rudolph, Michael C., Deoliveira, Divino, Anderson, Steven M., Abel, E. Dale, Chen, Benny J., Hale, Laura P., Rathmell, Jeffrey C.
Publicado em 2014

Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages

Por Schmidt, Elyse A., Fee, Brian E., Henry, Stanley C., Nichols, Amanda G., Shinohara, Mari L., Rathmell, Jeffrey C., MacIver, Nancie J., Coers, Jörn, Ilkayeva, Olga R., Koves, Timothy R., Taylor, Gregory A.
Publicado no J Biol Chem (2017)

Foxp3 and Toll-like receptor signaling balance T(reg) cell anabolic metabolism for suppression

Por Gerriets, Valerie A, Kishton, Rigel J, Johnson, Marc O, Cohen, Sivan, Siska, Peter J, Nichols, Amanda G, Warmoes, Marc O, de Cubas, Aguirre A, MacIver, Nancie J, Locasale, Jason W, Turka, Laurence A, Wells, Andrew D, Rathmell, Jeffrey C
Publicado no Nat Immunol (2016)

Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation

Por Michalek, Ryan D., Gerriets, Valerie A., Nichols, Amanda G., Inoue, Makoto, Kazmin, Dmitri, Chang, Ching-Yi, Dwyer, Mary A., Nelson, Erik R., Pollizzi, Kristen N., Ilkayeva, Olga, Giguere, Vincent, Zuercher, William J., Powell, Jonathan D., Shinohara, Mari L., McDonnell, Donald P., Rathmell, Jeffrey C.
Publicado em 2011

HIF-1α regulates the response of primary sarcomas to radiation therapy through a cell autonomous mechanism

Por Zhang, Minsi, Qiu, Qiong, Li, Zhizhong, Sachdeva, Mohit, Min, Hooney, Cardona, Diana M., DeLaney, Thomas F., Han, Tracy, Ma, Yan, Luo, Lixia, Ilkayeva, Olga R., Lui, Ki, Nichols, Amanda G., Newgard, Christopher B., Kastan, Michael B., Rathmell, Jeffrey C., Dewhirst, Mark W., Kirsch, David G.
Publicado no Radiat Res (2015)

AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival

Por Kishton, Rigel J., Barnes, Carson E., Nichols, Amanda G., Cohen, Sivan, Gerriets, Valerie A., Siska, Peter J., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, de Cubas, Aguirre A., Liu, Tingyu, Warmoes, Marc O., Abel, E. Dale, Yeoh, Allen Eng Juh, Gershon, Timothy R., Rathmell, W. Kimryn, Richards, Kristy L., Locasale, Jason W., Rathmell, Jeffrey C.
Publicado no Cell Metab (2016)

Metabolic programming and PDHK1 control CD4(+) T cell subsets and inflammation

Por Gerriets, Valerie A., Kishton, Rigel J., Nichols, Amanda G., Macintyre, Andrew N., Inoue, Makoto, Ilkayeva, Olga, Winter, Peter S., Liu, Xiaojing, Priyadharshini, Bhavana, Slawinska, Marta E., Haeberli, Lea, Huck, Catherine, Turka, Laurence A., Wood, Kris C., Hale, Laura P., Smith, Paul A., Schneider, Martin A., MacIver, Nancie J., Locasale, Jason W., Newgard, Christopher B., Shinohara, Mari L., Rathmell, Jeffrey C.
Publicado no J Clin Invest (2014)