Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4(+) T Cell Subsets

Stimulated CD4(+) T lymphocytes can differentiate into effector T cell (Teff) or inducible regulatory T cell (Treg) subsets with specific immunological roles. We show that Teff and Treg require distinct metabolic programs to support these functions. Th1, Th2, and Th17 cells expressed high surface le...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Michalek, Ryan D., Gerriets, Valerie A., Jacobs, Sarah R., Macintyre, Andrew N., MacIver, Nancie J., Mason, Emily F., Sullivan, Sarah A., Nichols, Amanda G., Rathmell, Jeffrey C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198034/
https://ncbi.nlm.nih.gov/pubmed/21317389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003613
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak