Energy metabolism in neurodevelopment and medulloblastoma

Por Tech, Katherine, Gershon, Timothy R.
Publicado no Transl Pediatr (2015)

Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma

Por Tech, Katherine, Deshmukh, Mohanish, Gershon, Timothy R.
Publicado em 2014

Temporally Regulated Neural Crest Transcription Factors Distinguish Neuroectodermal Tumors of Varying Malignancy and Differentiation

Por Gershon, Timothy R, Oppenheimer, Orit, Chin, Steven S, Gerald, William L
Publicado em 2005

Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum

Por Gershon, Timothy R, Crowther, Andrew J, Liu, Hedi, Miller, C Ryan, Deshmukh, Mohanish
Publicado em 2013

Bax-deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation

Por Garcia, Idoia, Crowther, Andrew J., Gama, Vivian, Miller, C. Ryan, Deshmukh, Mohanish, Gershon, Timothy R.
Publicado em 2012

Enteric Neural Crest Differentiation in Ganglioneuromas Implicates Hedgehog Signaling in Peripheral Neuroblastic Tumor Pathogenesis

Por Gershon, Timothy R., Shirazi, Arash, Qin, Li-Xuan, Gerald, William L., Kenney, Anna M., Cheung, Nai-Kong
Publicado em 2009

Tonic Activation of Bax Primes Neural Progenitors for Rapid Apoptosis through a Mechanism Preserved in Medulloblastoma

Por Crowther, Andrew J., Gama, Vivian, Bevilacqua, Ariana, Chang, Sha X., Yuan, Hong, Deshmukh, Mohanish, Gershon, Timothy R.
Publicado em 2013

ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation

Por Lang, Patrick Y., Nanjangud, Gouri J., Sokolsky-Papkov, Marina, Shaw, Christine, Hwang, Duhyeong, Parker, Joel S., Kabanov, Alexander V., Gershon, Timothy R.
Publicado no Development (2016)

Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

Por Gershon, Timothy R, Crowther, Andrew J, Tikunov, Andrey, Garcia, Idoia, Annis, Ryan, Yuan, Hong, Miller, C Ryan, Macdonald, Jeffrey, Olson, James, Deshmukh, Mohanish
Publicado em 2013

Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum

Por Swahari, Vijay, Nakamura, Ayumi, Baran-Gale, Jeanette, Garcia, Idoia, Crowther, Andrew J., Sons, Robert, Gershon, Timothy R., Hammond, Scott, Sethupathy, Praveen, Deshmukh, Mohanish
Publicado no Cell Rep (2015)

ASC deficiency suppresses proliferation and prevents medulloblastoma incidence

Por Knight, Elizabeth R. W., Patel, Esita Y., Flowers, Cornelius A., Crowther, Andrew J., Ting, Jenny P., Miller, C. Ryan, Gershon, Timothy R., Deshmukh, Mohanish
Publicado no Oncogene (2014)

Radiation sensitivity in a preclinical mouse model of medulloblastoma relies on the function of the intrinsic apoptotic pathway

Por Crowther, Andrew, Ocasio, Jennifer, Fang, Fang, Meidinger, Jessica, Wu, Jaclyn, Deal, Allison M, Chang, Sha X., Yuan, Hong, Schmid, Ralf, Davis, Ian, Gershon, Timothy R.
Publicado no Cancer Res (2016)

Tbata modulates thymic stromal cell proliferation and thymus function

Por Flomerfelt, Francis A., El Kassar, Nahed, Gurunathan, Chandra, Chua, Kevin S., League, Stacy C., Schmitz, Sabrina, Gershon, Timothy R., Kapoor, Veena, Yan, Xiao-Yi, Schwartz, Ronald H., Gress, Ronald E.
Publicado em 2010

Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice

Por Williams, Scott E., Garcia, Idoia, Crowther, Andrew J., Li, Shiyi, Stewart, Alyssa, Liu, Hedi, Lough, Kendall J., O'Neill, Sean, Veleta, Katherine, Oyarzabal, Esteban A., Merrill, Joseph R., Shih, Yen-Yu Ian, Gershon, Timothy R.
Publicado no Development (2015)

Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma

Por Garcia, Idoia, Mayol, Gemma, Rodríguez, Eva, Suñol, Mariona, Gershon, Timothy R, Ríos, José, Cheung, Nai-Kong V, Kieran, Mark W, George, Rani E, Perez-Atayde, Antonio R, Casala, Carla, Galván, Patricia, de Torres, Carmen, Mora, Jaume, Lavarino, Cinzia
Publicado em 2010

AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival

Por Kishton, Rigel J., Barnes, Carson E., Nichols, Amanda G., Cohen, Sivan, Gerriets, Valerie A., Siska, Peter J., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, de Cubas, Aguirre A., Liu, Tingyu, Warmoes, Marc O., Abel, E. Dale, Yeoh, Allen Eng Juh, Gershon, Timothy R., Rathmell, W. Kimryn, Richards, Kristy L., Locasale, Jason W., Rathmell, Jeffrey C.
Publicado no Cell Metab (2016)