Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum

Maintenance of genomic integrity is critical during neurodevelopment, particularly in rapidly dividing cerebellar granule neuronal precursors that experience constitutive replication-associated DNA damage. As Dicer was recently recognized to have an unexpected function in the DNA damage response, we...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Swahari, Vijay, Nakamura, Ayumi, Baran-Gale, Jeanette, Garcia, Idoia, Crowther, Andrew J., Sons, Robert, Gershon, Timothy R., Hammond, Scott, Sethupathy, Praveen, Deshmukh, Mohanish
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716786/
https://ncbi.nlm.nih.gov/pubmed/26748703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.037
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