Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum

Maintenance of genomic integrity is critical during neurodevelopment, particularly in rapidly dividing cerebellar granule neuronal precursors that experience constitutive replication-associated DNA damage. As Dicer was recently recognized to have an unexpected function in the DNA damage response, we...

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Pubblicato in:Cell Rep
Autori principali: Swahari, Vijay, Nakamura, Ayumi, Baran-Gale, Jeanette, Garcia, Idoia, Crowther, Andrew J., Sons, Robert, Gershon, Timothy R., Hammond, Scott, Sethupathy, Praveen, Deshmukh, Mohanish
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716786/
https://ncbi.nlm.nih.gov/pubmed/26748703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.037
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