Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum

Maintenance of genomic integrity is critical during neurodevelopment, particularly in rapidly dividing cerebellar granule neuronal precursors that experience constitutive replication-associated DNA damage. As Dicer was recently recognized to have an unexpected function in the DNA damage response, we...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Swahari, Vijay, Nakamura, Ayumi, Baran-Gale, Jeanette, Garcia, Idoia, Crowther, Andrew J., Sons, Robert, Gershon, Timothy R., Hammond, Scott, Sethupathy, Praveen, Deshmukh, Mohanish
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716786/
https://ncbi.nlm.nih.gov/pubmed/26748703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.037
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