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Bcl-xL Is Essential for the Survival and Function of Differentiated Neurons in the Cortex That Control Complex Behaviors

Apoptosis plays an essential role during brain development, yet the precise mechanism by which this pathway is regulated in the brain remains unknown. In particular, mammalian cells are known to express multiple anti-apoptotic Bcl-2 family proteins. However, the cells of the developing brain could a...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nakamura, Ayumi, Swahari, Vijay, Plestant, Charlotte, Smith, Ikuko, McCoy, Eric, Smith, Spencer, Moy, Sheryl S., Anton, E. S., Deshmukh, Mohanish
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871982/
https://ncbi.nlm.nih.gov/pubmed/27194326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4247-15.2016
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