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Mcl-1 and Bcl-xL are essential for survival of the developing nervous system

During neurogenesis, proliferating neural precursor cells (NPC) exit the cell cycle and differentiate into postmitotic neurons. The proteins that regulate cell survival through the stages of differentiation, however, are still poorly understood. Here, we examined the roles of the anti-apoptotic Bcl-...

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Publicat a:Cell Death Differ
Autors principals: Fogarty, Lauren C., Flemmer, Robert T., Geizer, Brittany A., Licursi, Maria, Karunanithy, Ahila, Opferman, Joseph T., Hirasawa, Kensuke, Vanderluit, Jacqueline L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748126/
https://ncbi.nlm.nih.gov/pubmed/30361616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0225-1
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