Mcl-1 and Bcl-xL are essential for survival of the developing nervous system

During neurogenesis, proliferating neural precursor cells (NPC) exit the cell cycle and differentiate into postmitotic neurons. The proteins that regulate cell survival through the stages of differentiation, however, are still poorly understood. Here, we examined the roles of the anti-apoptotic Bcl-...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Fogarty, Lauren C., Flemmer, Robert T., Geizer, Brittany A., Licursi, Maria, Karunanithy, Ahila, Opferman, Joseph T., Hirasawa, Kensuke, Vanderluit, Jacqueline L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748126/
https://ncbi.nlm.nih.gov/pubmed/30361616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0225-1
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