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Mcl-1 and Bcl-xL are essential for survival of the developing nervous system

During neurogenesis, proliferating neural precursor cells (NPC) exit the cell cycle and differentiate into postmitotic neurons. The proteins that regulate cell survival through the stages of differentiation, however, are still poorly understood. Here, we examined the roles of the anti-apoptotic Bcl-...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Fogarty, Lauren C., Flemmer, Robert T., Geizer, Brittany A., Licursi, Maria, Karunanithy, Ahila, Opferman, Joseph T., Hirasawa, Kensuke, Vanderluit, Jacqueline L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748126/
https://ncbi.nlm.nih.gov/pubmed/30361616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0225-1
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