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A new way to treat brain tumors: Targeting proteins coded by microcephaly genes?: Brain tumors and microcephaly arise from opposing derangements regulating progenitor growth. Drivers of microcephaly could be attractive brain tumor targets

New targets for brain tumor therapies may be identified by mutations that cause hereditary microcephaly. Brain growth depends on the repeated proliferation of stem and progenitor cells. Microcephaly syndromes result from mutations that specifically impair the ability of brain progenitor or stem cell...

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Bibliographische Detailangaben
Veröffentlicht in:Bioessays
Hauptverfasser: Lang, Patrick Y., Gershon, Timothy R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910257/
https://ncbi.nlm.nih.gov/pubmed/29577351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700243
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