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The tumor vasculature an attractive CAR T cell target in solid tumors

T cells armed with a chimeric antigen receptor, CAR T cells, have shown extraordinary activity against certain B lymphocyte malignancies, when targeted towards the CD19 B cell surface marker. These results have led to the regulatory approval of two CAR T cell approaches. Translation of this result t...

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Detalhes bibliográficos
Publicado no:Angiogenesis
Main Authors: Akbari, Parvin, Huijbers, Elisabeth J. M., Themeli, Maria, Griffioen, Arjan W., van Beijnum, Judy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864117/
https://ncbi.nlm.nih.gov/pubmed/31628559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-019-09687-9
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