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Secreted frizzled-related protein 2: a key player in noncanonical Wnt signaling and tumor angiogenesis
Secreted frizzled-related proteins (SFRP) are glycoproteins containing a so-called frizzled-like cysteine-rich domain. This domain enables them to bind to Wnt ligands or frizzled (FzD) receptors, making potent regulators of Wnt signaling. As Wnt signaling is often altered in cancer, it is not surpri...
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| Publicado no: | Cancer Metastasis Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7897195/ https://ncbi.nlm.nih.gov/pubmed/33140138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09941-3 |
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