Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

BACKGROUND: While aerobic glycolysis is linked to unconstrained proliferation in cancer, less is known about its physiological role. Why this metabolic program that promotes tumor growth is preserved in the genome has thus been unresolved. We tested the hypothesis that aerobic glycolysis derives fro...

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Bibliografiska uppgifter
Huvudupphovsmän: Gershon, Timothy R, Crowther, Andrew J, Tikunov, Andrey, Garcia, Idoia, Annis, Ryan, Yuan, Hong, Miller, C Ryan, Macdonald, Jeffrey, Olson, James, Deshmukh, Mohanish
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782751/
https://ncbi.nlm.nih.gov/pubmed/24280485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-2
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