Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages

The immunity-related GTPases (IRGs) are a family of proteins that are induced by interferon (IFN)-γ and play pivotal roles in immune and inflammatory responses. IRGs ostensibly function as dynamin-like proteins that bind to intracellular membranes and promote remodeling and trafficking of those memb...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Schmidt, Elyse A., Fee, Brian E., Henry, Stanley C., Nichols, Amanda G., Shinohara, Mari L., Rathmell, Jeffrey C., MacIver, Nancie J., Coers, Jörn, Ilkayeva, Olga R., Koves, Timothy R., Taylor, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377780/
https://ncbi.nlm.nih.gov/pubmed/28154172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770735
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