Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages

The immunity-related GTPases (IRGs) are a family of proteins that are induced by interferon (IFN)-γ and play pivotal roles in immune and inflammatory responses. IRGs ostensibly function as dynamin-like proteins that bind to intracellular membranes and promote remodeling and trafficking of those memb...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Schmidt, Elyse A., Fee, Brian E., Henry, Stanley C., Nichols, Amanda G., Shinohara, Mari L., Rathmell, Jeffrey C., MacIver, Nancie J., Coers, Jörn, Ilkayeva, Olga R., Koves, Timothy R., Taylor, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377780/
https://ncbi.nlm.nih.gov/pubmed/28154172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770735
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