Measurement of Fatty Acid Oxidation Rates in Animal Tissues and Cell Lines

Por Huynh, Frank K., Green, Michelle F., Koves, Timothy R., Hirschey, Matthew D.
Publicado em 2014

Plasma acylcarnitines during insulin stimulation in humans are reflective of age-related metabolic dysfunction

Por Consitt, Leslie A., Koves, Timothy R., Muoio, Deborah M., Nakazawa, Masato, Newton, Christopher A., Houmard, Joseph A.
Publicado no Biochem Biophys Res Commun (2016)

Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes

Por Fisher-Wellman, Kelsey H., Davidson, Michael T., Narowski, Tara M., Lin, Chien-Te, Koves, Timothy R., Muoio, Deborah M.
Publicado no Cell Rep (2018)

Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle

Por Khodabukus, Alastair, Madden, Lauran, Prabhu, Neel K., Koves, Timothy R., Jackman, Christopher P., Muoio, Deborah M., Bursac, Nenad
Publicado no Biomaterials (2018)

Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans(1)(2)(3)

Por Kien, C Lawrence, Bunn, Janice Y, Stevens, Robert, Bain, James, Ikayeva, Olga, Crain, Karen, Koves, Timothy R, Muoio, Deborah M
Publicado em 2014

Metabolomic analysis reveals decreased skeletal muscle amino acid content and altered fatty acid handling in obese humans

Por Baker, Peter R., Boyle, Kristen E., Koves, Timothy R., Ilkayeva, Olga R., Muoio, Deborah M., Houmard, Joseph A., Friedman, Jacob E.
Publicado no Obesity (Silver Spring) (2015)

Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle

Por Barrientos, Tomasa, Laothamatas, Indira, Koves, Timothy R., Soderblom, Erik J., Bryan, Miles, Moseley, M. Arthur, Muoio, Deborah M., Andrews, Nancy C.
Publicado no EBioMedicine (2015)

Human, Tissue-Engineered, Skeletal Muscle Myobundles to Measure Oxygen Uptake and Assess Mitochondrial Toxicity

Por Davis, Brittany N.J., Santoso, Jeffrey W., Walker, Michaela J., Cheng, Cindy S., Koves, Timothy R., Kraus, William E., Truskey, George A.
Publicado no Tissue Eng Part C Methods (2017)

Metabolic profiling of PPARα(−/−) mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation

Por Makowski, Liza, Noland, Robert C., Koves, Timothy R., Xing, Weibing, Ilkayeva, Olga R., Muehlbauer, Michael J., Stevens, Robert D., Muoio, Deborah M.
Publicado em 2009

Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase

Por Ussher, John R., Koves, Timothy R., Jaswal, Jagdip S., Zhang, Liyan, Ilkayeva, Olga, Dyck, Jason R.B., Muoio, Deborah M., Lopaschuk, Gary D.
Publicado em 2009

Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Overexpression Increases Lipid Oxidation in Myocytes From Extremely Obese Individuals

Por Consitt, Leslie A., Bell, Jill A., Koves, Timothy R., Muoio, Deborah M., Hulver, Matthew W., Haynie, Kimberly R., Dohm, G. Lynis, Houmard, Joseph A.
Publicado em 2010

Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood(1)(2)(3)

Por Kien, C Lawrence, Bunn, Janice Y, Tompkins, Connie L, Dumas, Julie A, Crain, Karen I, Ebenstein, David B, Koves, Timothy R, Muoio, Deborah M
Publicado em 2013

Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis

Por Li, Lei O., Grevengoed, Trisha J., Paul, David S., Ilkayeva, Olga, Koves, Timothy R., Pascual, Florencia, Newgard, Christopher B., Muoio, Deborah M., Coleman, Rosalind A.
Publicado no Diabetes (2015)

Plasma MicroRNAs in Established Rheumatoid Arthritis Relate to Adiposity and Altered Plasma and Skeletal Muscle Cytokine and Metabolic Profiles

Por Andonian, Brian J., Chou, Ching-Heng, Ilkayeva, Olga R., Koves, Timothy R., Connelly, Margery A., Kraus, William E., Kraus, Virginia B., Huffman, Kim M.
Publicado no Front Immunol (2019)

Carnitine Insufficiency Caused by Aging and Overnutrition Compromises Mitochondrial Performance and Metabolic Control

Por Noland, Robert C., Koves, Timothy R., Seiler, Sarah E., Lum, Helen, Lust, Robert M., Ilkayeva, Olga, Stevens, Robert D., Hegardt, Fausto G., Muoio, Deborah M.
Publicado em 2009

Identification of a novel malonyl-CoA IC(50) for CPT-1: implications for predicting in vivo fatty acid oxidation rates

Por Smith, Brennan K., Perry, Christopher G.R., Koves, Timothy R., Wright, David C., Smith, Jeffrey C., Neufer, P. Darrell, Muoio, Deborah M., Holloway, Graham P.
Publicado em 2012

A Mitochondrial Progesterone Receptor Increases Cardiac Beta-Oxidation and Remodeling

Por Dai, Qunsheng, Likes, Creighton E, Luz, Anthony L, Mao, Lan, Yeh, Jason S, Wei, Zhengzheng, Kuchibhatla, Maragatha, Ilkayeva, Olga R, Koves, Timothy R, Price, Thomas M
Publicado no J Endocr Soc (2019)

Adipose acyl-CoA synthetase-1 (ACSL1) directs fatty acids towards β-oxidation and is required for cold thermogenesis

Por Ellis, Jessica M., Li, Lei O., Wu, Pei-Chi, Koves, Timothy R., Ilkayeva, Olga, Stevens, Robert D., Watkins, Steven M., Muoio, Deborah M., Coleman, Rosalind A.
Publicado em 2010

Metabolic profiling of muscle contraction in lean compared with obese rodents

Por Thyfault, John P., Cree, Melanie G., Tapscott, Edward B., Bell, Jill A., Koves, Timothy R., Ilkayeva, Olga, Wolfe, Robert R., Dohm, G. Lynis, Muoio, Deborah M.
Publicado em 2010

Re-patterning of Skeletal Muscle Energy Metabolism by Fat Storage-inducing Transmembrane Protein 2

Por Miranda, Diego A., Koves, Timothy R., Gross, David A., Chadt, Alexandra, Al-Hasani, Hadi, Cline, Gary W., Schwartz, Gary J., Muoio, Deborah M., Silver, David L.
Publicado em 2011