Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase

OBJECTIVE: Whereas an impaired ability to oxidize fatty acids is thought to contribute to intracellular lipid accumulation, insulin resistance, and cardiac dysfunction, high rates of fatty acid oxidation could also impair glucose metabolism and function. We therefore determined the effects of diet-i...

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Detalhes bibliográficos
Main Authors: Ussher, John R., Koves, Timothy R., Jaswal, Jagdip S., Zhang, Liyan, Ilkayeva, Olga, Dyck, Jason R.B., Muoio, Deborah M., Lopaschuk, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712785/
https://ncbi.nlm.nih.gov/pubmed/19478144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0011
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