Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis

The impaired capacity of skeletal muscle to switch between the oxidation of fatty acid (FA) and glucose is linked to disordered metabolic homeostasis. To understand how muscle FA oxidation affects systemic glucose, we studied mice with a skeletal muscle–specific deficiency of long-chain acyl-CoA syn...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Li, Lei O., Grevengoed, Trisha J., Paul, David S., Ilkayeva, Olga, Koves, Timothy R., Pascual, Florencia, Newgard, Christopher B., Muoio, Deborah M., Coleman, Rosalind A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274800/
https://ncbi.nlm.nih.gov/pubmed/25071025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1070
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