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Adipose acyl-CoA synthetase-1 (ACSL1) directs fatty acids towards β-oxidation and is required for cold thermogenesis
Acyl-CoA synthetase-1 (ACSL) contributes 80% of total ACSL activity in adipose tissue and was believed to be essential for the synthesis of triacylglycerol. We predicted that an adipose-specific knockout of ACSL1 (Acsl1(A−/−)) would be lipodystrophic, but, compared to controls, Acsl1(A−/−) mice had...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910420/ https://ncbi.nlm.nih.gov/pubmed/20620995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.05.012 |
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