Mapping the pathways of resistance to targeted therapies

por Wood, Kris C.
Publicado no Cancer Res (2015)

Overcoming MCL-1-driven adaptive resistance to targeted therapies

por Wood, Kris C.
Publicado no Nat Commun (2020)

Growth signaling at the nexus of stem cell life and death

por Wood, Kris C., Sabatini, David M.
Publicado em 2009

Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes

por Singleton, Katherine R., Wood, Kris C.
Publicado no Genes Cancer (2016)

Label propagation defines signaling networks associated with recurrently mutated cancer genes

por Cakir, Merve, Mukherjee, Sayan, Wood, Kris C.
Publicado no Sci Rep (2019)

Bayesian Approximate Kernel Regression with Variable Selection

por Crawford, Lorin, Wood, Kris C., Zhou, Xiang, Mukherjee, Sayan
Publicado no J Am Stat Assoc (2018)

Controlling interlayer diffusion to achieve sustained, multiagent delivery from layer-by-layer thin films

por Wood, Kris C., Chuang, Helen F., Batten, Robert D., Lynn, David M., Hammond, Paula T.
Publicado em 2006

Electroactive controlled release thin films

por Wood, Kris C., Zacharia, Nicole S., Schmidt, Daniel J., Wrightman, Stefani N., Andaya, Brian J., Hammond, Paula T.
Publicado em 2008

RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis

por Winter, Peter S., Sarosiek, Kristopher A., Lin, Kevin H., Meggendorfer, Manja, Schnittger, Susanne, Letai, Anthony, Wood, Kris C.
Publicado no Sci Signal (2014)

An Acoustofluidic Trap and Transfer Approach for Organizing a High Density Single Cell Array

por Ohiri, Korine A., Kelly, Sean T., Motschman, Jeffrey D., Lin, Kevin H., Wood, Kris C., Yellen, Benjamin B.
Publicado no Lab Chip (2018)

Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance

por Ali, Moiez, Kaltenbrun, Erin, Anderson, Gray R., Stephens, Sarah Jo, Arena, Sabrina, Bardelli, Alberto, Counter, Christopher M., Wood, Kris C.
Publicado no Nat Commun (2017)

Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity

por Soderquist, Ryan S., Crawford, Lorin, Liu, Esther, Lu, Min, Agarwal, Anika, Anderson, Gray R., Lin, Kevin H., Winter, Peter S., Cakir, Merve, Wood, Kris C.
Publicado no Nat Commun (2018)

Targeting MCL-1/BCL-X(L) Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia

por Lin, Kevin H., Winter, Peter S., Xie, Abigail, Roth, Cullen, Martz, Colin A., Stein, Elizabeth M., Anderson, Gray R., Tingley, Jennifer P., Wood, Kris C.
Publicado no Sci Rep (2016)

Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis

por Liberti, Maria V., Allen, Annamarie E., Ramesh, Vijyendra, Dai, Ziwei, Singleton, Katherine R., Guo, Zufeng, Liu, Jun O., Wood, Kris C., Locasale, Jason W.
Publicado no J Biol Chem (2020)

Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors

por Anderson, Gray R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.
Publicado no Nat Commun (2018)

MicroSCALE Screening Reveals Genetic Modifiers of Therapeutic Response in Melanoma

por Wood, Kris C., Konieczkowski, David J., Johannessen, Cory M., Boehm, Jesse S., Tamayo, Pablo, Botvinnik, Olga B., Mesirov, Jill P., Hahn, William C., Root, David E., Garraway, Levi A., Sabatini, David M.
Publicado em 2012

ERRα Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer

por Park, Sunghee, Chang, Ching-yi, Safi, Rachid, Liu, Xiaojing, Baldi, Robert, Jasper, Jeff S., Anderson, Grace R., Liu, Tingyu, Rathmell, Jeffrey C., Dewhirst, Mark W., Wood, Kris C., Locasale, Jason W., McDonnell, Donald P.
Publicado no Cell Rep (2016)

Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers

por Misale, Sandra, Bozic, Ivana, Tong, Jingshan, Peraza-Penton, Ashley, Lallo, Alice, Baldi, Federica, Lin, Kevin H., Truini, Mauro, Trusolino, Livio, Bertotti, Andrea, Di Nicolantonio, Federica, Nowak, Martin A., Zhang, Lin, Wood, Kris C., Bardelli, Alberto
Publicado no Nat Commun (2015)

Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection

por Price, Alexander M, Dai, Joanne, Bazot, Quentin, Patel, Luv, Nikitin, Pavel A, Djavadian, Reza, Winter, Peter S, Salinas, Cristina A, Barry, Ashley Perkins, Wood, Kris C, Johannsen, Eric C, Letai, Anthony, Allday, Martin J, Luftig, Micah A
Publicado no eLife (2017)

Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models

por Manzari, Mandana T., Anderson, Grace R., Lin, Kevin H., Soderquist, Ryan S., Çakir, Merve, Zhang, Mitchell, Moore, Chandler E., Skelton, Rachel N., Fèvre, Maréva, Li, Xinghai, Bellucci, Joseph J., Wardell, Suzanne E., Costa, Simone A., Wood, Kris C., Chilkoti, Ashutosh
Publicado no Sci Adv (2019)